Annual report pursuant to Section 13 and 15(d)

STOCK-BASED COMPENSATION (Details 1)

v3.8.0.1
STOCK-BASED COMPENSATION (Details 1) - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation $ 758,757 $ 529,159
Employee and director stock options and stock grants [Member]    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation 758,757 529,497
Employee and director stock options and stock grants [Member] | Research and development [Member]    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation 147,821 58,044
Employee and director stock options and stock grants [Member] | General and administrative [Member]    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation 610,936 471,453
Non-employee consultant stock option grants [Member]    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation 0 (338)
Non-employee consultant stock option grants [Member] | Research and development [Member]    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation 0 (338)
Non-employee consultant stock option grants [Member] | General and administrative [Member]    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation $ 0 $ 0