Annual report pursuant to Section 13 and 15(d)

INCOME TAXES (Tables)

v3.8.0.1
INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2017
Income Tax Disclosure [Abstract]  
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
 
 
2017
 
2016
 
 
 
 
 
 
 
 
 
Tax provision (benefit)
 
 
 
 
 
 
 
Current
 
 
 
 
 
 
 
Federal
 
$
 
$
 
State
 
 
 
 
 
Total current
 
 
 
 
 
 
 
 
 
 
 
 
 
Deferred
 
 
 
 
 
 
 
Federal
 
 
13,626,404
 
 
(4,053,114)
 
State
 
 
1,969,262
 
 
99,883
 
Total deferred
 
 
15,595,666
 
 
(3,953,231)
 
 
 
 
 
 
 
 
 
Change in valuation allowance
 
 
(15,595,666)
 
 
3,953,231
 
Total
 
$
 
$
 
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Deferred tax assets consisted of the following at December 31:
 
 
 
2017
 
2016
 
 
 
 
 
 
 
 
 
Deferred tax assets
 
 
 
 
 
 
 
Federal net operating loss
 
$
24,353,504
 
$
36,472,996
 
Federal research and development tax credit carryforwards
 
 
4,947,879
 
 
3,808,862
 
State net operating losses and tax credit carryforwards
 
 
1,589,927
 
 
2,628,006
 
Capitalized research and development expenses
 
 
5,772,165
 
 
8,834,640
 
Stock-based compensation expense
 
 
1,445,078
 
 
2,162,703
 
Depreciable assets
 
 
166,793
 
 
 
Other
 
 
121,680
 
 
235,681
 
Total deferred tax assets
 
 
38,397,026
 
 
54,142,888
 
 
 
 
 
 
 
 
 
Deferred tax liabilities
 
 
 
 
 
 
 
Depreciable assets
 
 
 
 
(150,196)
 
Total deferred tax liabilities
 
 
 
 
(150,196)
 
 
 
 
 
 
 
 
 
Net deferred tax assets
 
 
38,397,026
 
 
53,992,692
 
Less– valuation allowance
 
 
(38,397,026)
 
 
(53,992,692)
 
Total deferred tax assets
 
$
 
$
 
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
A reconciliation of income taxes computed using the U.S. federal statutory rate to that reflected in operations is as follows:
 
 
 
Year ended December 31,
 
 
 
2017
 
2016
 
Income tax benefit using U.S. federal statutory rate
 
 
34.00
%
 
34.00
%
State income taxes
 
 
(9.58)
%
 
(1.07)
%
Permanent items
 
 
(2.55)
%
 
17.88
%
Federal tax credits
 
 
8.43
%
 
9.55
%
Change in valuation allowance
 
 
115
%
 
(63.97)
%
Federal rate change
 
 
(143.50)
%
 
 
Other
 
 
(1.80)
%
 
3.61
%
Total
 
 
0.00
%
 
0.00
%