STOCK-BASED COMPENSATION (Details) - USD ($)  | 
3 Months Ended | 9 Months Ended | ||
|---|---|---|---|---|
Sep. 30, 2018  | 
Sep. 30, 2017  | 
Sep. 30, 2018  | 
Sep. 30, 2017  | 
|
| Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items] | ||||
| Total stock-based compensation | $ 163,896 | $ 176,324 | $ 512,913 | $ 573,084 | 
| Employee and director stock option grants [Member] | Research and development [Member] | ||||
| Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items] | ||||
| Total stock-based compensation | 31,409 | 46,059 | 102,161 | 102,780 | 
| Employee and director stock option grants [Member] | General and administrative [Member] | ||||
| Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items] | ||||
| Total stock-based compensation | $ 132,487 | $ 130,265 | $ 410,752 | $ 470,304 |