Quarterly report pursuant to Section 13 or 15(d)

STOCKHOLDERS' EQUITY (Details)

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STOCKHOLDERS' EQUITY (Details)
 3 Months Ended
Mar. 31, 2016
$ / shares
shares
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 831,056
October 2015 Private Placement [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 150,003 [1]
Exercise Price (in dollars per share) | $ / shares $ 28.30 [1]
Warrants Expiration Date Apr. 01, 2021 [1]
October 2015 Registered Offering [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 48,274 [2]
Exercise Price (in dollars per share) | $ / shares $ 0 [2]
Warrants Expiration Date Oct. 01, 2020 [2]
October 2015 Offering - Placement Agent [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 3,750
Exercise Price (in dollars per share) | $ / shares $ 28.3
Warrants Expiration Date Oct. 01, 2020
August 2014 Public Offering [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 504,019 [1]
Exercise Price (in dollars per share) | $ / shares $ 46.8 [1]
Warrants Expiration Date Aug. 20, 2019 [1]
February 2013 Public Offering [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 55,000 [1]
Exercise Price (in dollars per share) | $ / shares $ 22 [1]
Warrants Expiration Date Feb. 20, 2018 [1]
February 2013 Public Offering - Placement Agents [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 3,854
Exercise Price (in dollars per share) | $ / shares $ 125
Warrants Expiration Date Feb. 04, 2018
November 2012 Private Placement [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 5,000
Exercise Price (in dollars per share) | $ / shares $ 250
Warrants Expiration Date Nov. 02, 2017
June 2012 Public Offering [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 14,910
Exercise Price (in dollars per share) | $ / shares $ 250
Warrants Expiration Date Jun. 13, 2017
December 2011 Underwritten Offering [Member]  
Class of Warrant or Right [Line Items]  
Number of Shares Issuable Upon Exercise of Outstanding Warrants (in shares) 46,246
Exercise Price (in dollars per share) | $ / shares $ 120
Warrants Expiration Date Dec. 06, 2016
[1] These warrants have a certain type of cash settlement feature or their exercise prices are subject to adjustment for “down-rounds” and the warrants have been accounted for as derivative instruments as described in Note 3, with the exception of 9,704 warrants issued in August 2014.
[2] These warrants are pre-funded, and the number of shares for which the warrant may be exercised are subject to adjustment for “down-rounds” and the warrants have been accounted for as derivative instruments as described in Note 3.