Annual report pursuant to Section 13 and 15(d)

INCOME TAXES (Details 1)

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INCOME TAXES (Details 1) (USD $)
Dec. 31, 2013
Dec. 31, 2012
Deferred tax assets    
Federal net operating loss $ 25,731,718 $ 22,343,084
Federal research and development tax credit carryforwards 2,480,417 1,969,426
State net operating loss 2,070,642 2,252,566
State research and development tax credit carryforwards 724,200 633,571
Capitalized research and development expenses 11,128,803 11,068,868
Stock-based compensation expense 1,599,005 842,174
Intangible assets 380,339 440,556
Charitable contribution carryforwards 34,850 43,350
Accrued liabilities 26,112 25,199
Total deferred tax assets 44,176,086 39,618,794
Deferred tax liabilities    
Depreciable assets (257,314) (271,049)
Total deferred tax liabilities (257,314) (271,049)
Net deferred tax assets 43,918,772 39,347,745
Less valuation allowance (43,918,772) (39,347,745)
Total deferred tax assets $ 0 $ 0