Annual report [Section 13 and 15(d), not S-K Item 405]

CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT)

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CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
Pre-funded warrants
Common Stock
Pre-funded warrants
Additional Paid-In Capital
Pre-funded warrants
Preferred Stock
Series E-2 Preferred Stock
Preferred Stock
Series E-3 preferred stock
Preferred Stock
Series E-4 preferred stock
Preferred Stock
Common Stock
Series E-2 Preferred Stock
Common Stock
Series E-3 preferred stock
Common Stock
Series E-4 preferred stock
Common Stock
Additional Paid-In Capital
Series E-2 Preferred Stock
Additional Paid-In Capital
Series E-3 preferred stock
Additional Paid-In Capital
Series E-4 preferred stock
Additional Paid-In Capital
Accumulated Deficit
Series D preferred stock
Series E-2 Preferred Stock
Series E-4 preferred stock
Total
Balance beginning at Dec. 31, 2022                     $ 94       $ 168,143,557 $ (159,990,407)       $ 8,153,244
Balance beginning (in shares) at Dec. 31, 2022                     9,385,272                  
Balance beginning Series D preferred stock at Dec. 31, 2022                                 $ 1,382,023      
Balance beginning Series D preferred stock (in shares) at Dec. 31, 2022                                 111.11      
Stock-based compensation                             2,410,288         2,410,288
Exercise of warrants into common shares                     $ 12       2,467,210         $ 2,467,222
Exercise of warrants into common shares (in shares)                     1,197,622                  
Conversion of preferred stock to common stock             $ (13,142,368)       $ 99       13,142,269          
Conversion of preferred stock to common stock (in shares)             (905.24)       9,947,684                  
Reclassification of pre-funded warrants to liability liability   $ (3,239,112) $ (3,239,112)                                  
Stock awards                     $ 2       (2)          
Stock awards (in shares)                     213,532                 1,617,000
Fair value of the warrants allocated to preferred stock       $ 17,820,000                           $ 17,820,000    
Issuance of preferred stock, net of issuance costs (in shares)       1,225                                
Net loss                               (42,770,610)       $ (42,770,610)
Balance ending Series D preferred stock at Dec. 31, 2023                                 $ 1,382,023      
Balance ending Series D preferred stock (in shares) at Dec. 31, 2023                                 111.11      
Balance ending at Dec. 31, 2023             $ 4,677,632       $ 207       182,924,210 (202,761,017)       (15,158,968)
Balance ending (in shares) at Dec. 31, 2023             319.76       20,744,110                  
Stock-based compensation                             4,272,780         4,272,780
Exercise of warrants into common shares $ 11 $ 3,972,529 $ 3,972,540               $ 5       2,298,138         2,298,143
Exercise of warrants into common shares (in shares) 1,079,132                   547,177                  
Exercise of warrants for preferred stock, net of issuance costs             $ 47,577,000                         $ 47,577,000
Exercise of warrants for preferred stock, net of issuance costs (in shares)             2,205                          
Conversion of preferred stock to common stock       $ (4,156,854) $ (47,577,000) $ (15,914,632)   $ 31 $ 139 $ 68   $ 4,156,823 $ 47,576,861 $ 15,914,564            
Conversion of preferred stock to common stock (in shares)       (284) (2,205) (1,610)   3,122,637 13,846,141 6,739,919                    
Stock awards (in shares)                                       3,063,500
Fair value of the warrants allocated to preferred stock           $ (15,914,632)                         $ (15,914,632)  
Issuance of preferred stock, net of issuance costs (in shares)           1,610                            
Stock option exercise into common stock (in shares)                     767                 1,667
Retired shares (in shares)                     (8)                  
Net loss                               (44,581,446)       $ (44,581,446)
Balance ending Series D preferred stock at Dec. 31, 2024                                 $ 1,382,023      
Balance ending Series D preferred stock (in shares) at Dec. 31, 2024                                 111.11      
Balance ending at Dec. 31, 2024             $ 520,778       $ 461       $ 261,115,905 $ (247,342,463)       $ 14,294,681
Balance ending (in shares) at Dec. 31, 2024             35.6       46,079,875