Quarterly report pursuant to Section 13 or 15(d)

STOCK-BASED COMPENSATION (Details)

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STOCK-BASED COMPENSATION (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]        
Total stock-based compensation $ 419,953 $ 200,617 $ 723,758 $ 325,181
Employee and director stock option grants | Research and development        
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]        
Total stock-based compensation 44,499 41,400 86,427 70,795
Employee and director stock option grants | General and administrative        
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]        
Total stock-based compensation $ 375,454 $ 159,217 $ 637,331 $ 254,386