Annual report pursuant to Section 13 and 15(d)

STOCK-BASED COMPENSATION (Details)

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STOCK-BASED COMPENSATION (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation $ 1,124,190 $ 467,541
Employee and director stock option grants | Research and development    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation 117,805 72,579
Employee and director stock option grants | General and administrative    
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items]    
Total stock-based compensation $ 1,006,385 $ 394,962