Quarterly report pursuant to Section 13 or 15(d)

STOCK-BASED COMPENSATION (Tables)

v3.8.0.1
STOCK-BASED COMPENSATION (Tables)
 3 Months Ended
Mar. 31, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block]
The following table summarizes amounts charged to expense for stock-based compensation related to employee and director stock option grants and recorded in connection with stock options granted to non-employee consultants:
 
 
 
Three Months Ended
March 31,
 
 
 
2018
 
2017
 
 
 
 
 
 
 
 
 
Employee and director stock option grants:
 
 
 
 
 
 
 
Research and development
 
$
34,127
 
$
16,648
 
General and administrative
 
 
139,311
 
 
149,026
 
Total stock-based compensation
 
$
173,438
 
$
165,674
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
A summary of stock option activity is as follows:
 
 
 
Number of 
Shares Issuable 
Upon Exercise 
of Outstanding 
Options
 
Weighted
Average
Exercise Price
 
Weighted
Average
Remaining
Contracted
Term in
Years
 
Aggregate 
Intrinsic 
Value
 
Outstanding at December 31, 2017
 
 
531,729
 
$
6.55
 
 
 
 
 
 
 
Granted
 
 
—
 
$
—
 
 
 
 
 
 
 
Expired
 
 
(4,350)
 
$
48.57
 
 
 
 
 
 
 
Forfeited
 
 
(17,987)
 
$
1.89
 
 
 
 
 
 
 
Outstanding at March 31, 2018
 
 
509,392
 
$
6.36
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Exercisable, March 31, 2018
 
 
278,499
 
$
8.40
 
 
7.75
 
$
—
 
Unvested, March 31, 2018
 
 
230,893
 
$
3.89
 
 
8.48
 
$
—
 
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
A summary of restricted stock activity is as follows:
 
Outstanding at December 31, 2017
 
380,000
 
Granted
 
—
 
Vested
 
(93,332)
 
Outstanding at March 31, 2018
 
286,668